Our mission is to develop next-generation, label-free optical imaging technologies that enable real-time visualization of molecular dynamics at the nanometer and microsecond scales within living cells. Through interdisciplinary innovation at the interface of physics, engineering, and biology, we aim to uncover the fundamental biophysical principles that govern cellular organization, gene regulation, and host–pathogen interactions. By extending the accessibility and applicability of these imaging tools to the broader life science and medical research communities, our work aspires to catalyze transformative insights into human health, disease mechanisms, and therapeutic interventions.

2026-01-16     ▏Congratulations to Yi-Jhen, Yan-Hsien, and Hsiang-Yu!

2026-01-02    ▏Our work on AI-assisted label-free 3D chromatin optical imaging is published

2025-12-05    ▏Our work on transmission-based mass photometry is published

2025-08-01    ▏Open Position – Postdoc and RA in Bioimaging and Biophysics

2025-05-07   ▏Hsiang-Yu wins Best Poster Award

2025-02-26   ▏Our work on the simple implementation of iSCAT using low-coherence light is published

2024-09-01   ▏Josephine Liang wins the 2024 IAMS Summer Internship Award

2024-07-23   ▏Dr. Hsieh wins the Young Investigator Award

2024-06-11     ▏Chih-Chen wins CTCI Outstanding Physics Undergraduate Award

2024 -01-31    ▏Chih-Chen wins the Best Poster Award at TPS 2024